ONE ProHeart 12 Shot
ONE Year of Protection
Ask Your Vet About the ONE

ProHeart 12 is the only FDA-approved product that prevents heartworm disease in dogs for 1 full year with just 1 shot given by your vet. At the time of the shot, ProHeart 12 also treats hookworms.* ProHeart 12 is for use in healthy dogs 12 months of age and older.

*ProHeart 12 is indicated for the treatment of existing larval and adult hookworm (Ancylostoma caninum and Uncinaria stenocephala) infections.

On average, the price of a ProHeart 12 shot is about the same as 12 months’ worth of a monthly heartworm disease preventative. Cost may vary depending on how much your dog weighs. Ask your vet for details.

ProHeart 12 can be used in healthy dogs 12 months of age and older. Talk with your vet about ProHeart 12 for your dog.

Yes. In fact, in a clinical study with client-owned dogs, ProHeart 12 had a similar adverse event profile to Heartgard Plus. The most common side effects were vomiting, diarrhea, and lethargy. As with all medications, adverse events are possible. Your vet will determine if your dog is a candidate for Proheart 12

ProHeart 12 provides 1 full year of heartworm disease prevention in just 1 shot. The active ingredient, moxidectin, is contained in slow-dissolving microspheres that are stored in your dog’s fat-storing connective tissue (a.k.a. adipose tissue). The medicine is then released evenly over 1 year’s time, keeping your buddy consistently protected from heartworms. Cool, right?

Heartworm disease is serious and potentially fatal—and a single bite from an infected mosquito can cause it in your dog. See the basics about heartworm disease, including your dog’s risk and some of the signs and symptoms.

No, ProHeart 12 is not a vaccine because it does not stimulate the production of antibodies. ProHeart 12 is an injection of preventative medicine that slowly releases over time in your dog’s body.

ProHeart 6 provides 6 months of heartworm disease prevention for dogs and ProHeart 12 provides 1 full year of heartworm disease prevention for dogs. Dogs older than 6 months but less than 1 year old should be given ProHeart 6.

It’s important to know if your dog has heartworms before starting a new heartworm product or switching to a different one. Not sure when your dog last had a heartworm test? Check with your vet before giving any heartworm medication—not just when starting a new product or switching.

Of course we all hope that won’t happen! But if it does, your vet will want to start by running a different test to confirm the diagnosis. If that test also shows a positive result, your vet will talk with you about a treatment plan.

Talk with your vet about switching to ProHeart 12 from another heartworm disease preventative.